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HELO Trial: Energy-Based Therapies vs. Conventional Hemorrhoidectomy for Grade III Hemorrhoids
Sponsor: Chang Gung Memorial Hospital
Summary
This prospective, multicenter study compares the efficacy and functional outcomes of three surgical treatments for symptomatic Goligher Grade III internal hemorrhoids: Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy (HET), and conventional closed hemorrhoidectomy (Ferguson technique). Due to strong patient preferences in hemorrhoidal surgery, this study utilizes a pragmatic, preference-tolerant design. Eligible patients will undergo standardized counseling and select their preferred treatment arm. The study aims to evaluate whether minimally invasive energy-based therapies offer superior postoperative pain relief and faster functional recovery compared to conventional hemorrhoidectomy
Official title: Hemorrhoidectomy, Energy-Based, and Laser Outcomes in Grade III Hemorrhoids: A Prospective, Multicenter, Preference-Based Comparative Study
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-03-01
Completion Date
2028-03-01
Last Updated
2026-01-12
Healthy Volunteers
No
Interventions
Laser Hemorrhoidoplasty (LHP)
1470nm or 980nm diode laser ablation
Hemorrhoid Energy Therapy (HET)
Bipolar radiofrequency coagulation using HET™ system
Ferguson Hemorrhoidectomy
Standard closed excisional hemorrhoidectomy
Locations (1)
Chang Gung Memorial Hospital, Linkou Branch
Taoyuan District, Taiwan