Clinical Research Directory

Inclusion Criteria: 1. Patient who will give verbal \& written will informed consent. 2. Pregnant women between 18 and 40 years old of age 3. Singleton pregnancy 4. Gestational age will be confirmed by first trimester ultrasound scan (\<14 weeks). 5. Gestational age between 24 and 34 weeks . 6. Threatened preterm labor which is defined as: Presence of at least one uterine contraction every 10 minutes lasting ≥30 seconds . Cervical dilatation ≤3 cm . Cervical effacement \<80%. Exclusion Criteria: Obstetric: 1. Ruptured membranes 2. Clinical evidence of Chorioamnionitis. 3. Fetal compromise on evaluation. 4. Severe obstetric complications (e.g., severe Preeclampsia, Eclampsia). 5. Diagnosed intrauterine growth restriction (IUGR). 6. Congenital fetal anomalies. 7. Multiple pregnancies. 8. Prior cervical surgery (e.g., cone biopsy, cerclage). Non-Obstetric: 1. Significant maternal medical disorders (e.g., chronic hypertension, diabetes mellitus, liver dysfunction). 2. Severe non-obstetric complications (e.g., acute abdomen).