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RECRUITING
NCT07336251
NA

Transcranial Magnetic Stimulation in Veterans With PTSD

Sponsor: White River Junction Veterans Affairs Medical Center

View on ClinicalTrials.gov

Summary

With this research investigators hope to begin to understand how rTMS can improve posttraumatic stress disorder (PTSD) symptoms. TMS improves PTSD through two interrelated mechanisms: change in brain limbic system function and change in systemic inflammatory activation. Participants who decide to join this study, will receive ten rTMS treatments. All participants will undergo a 40-minute rTMS procedure with a member of the study team 10 times over 2-4 weeks. Participants will undergo fMRI scans of the head in order to help researchers better understand potential effects of rTMS on brain activity. In addition, participants will be asked to give two breath and blood samples to look for signs of general inflammation.

Official title: Transcranial Magnetic Stimulation in Veterans With PTSD: A Pilot Study to Examine Mechanism of Effect

Key Details

Gender

All

Age Range

19 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2026-01-15

Completion Date

2027-01

Last Updated

2026-01-21

Healthy Volunteers

No

Interventions

DEVICE

Transcranial Magnetic Stimulation

10 sessions of low frequency rTMS (1Hz) applied to the right dorsolateral prefrontal cortex.

Locations (1)

White River Junction VA Hospital

White River Junction, Vermont, United States