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RECRUITING
NCT07336368
PHASE3

Topical Cryotherapy and Keloid/Hypertrophic Scars

Sponsor: Sonal Choudhary

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to determine whether the application of brief topical cryotherapy immediately before intralesional corticosteroid injections can reduce pain and injection resistance during routine treatment of keloid and hypertrophic scars in adult patients. The main questions it aims to answer are: Does topical cryotherapy applied before intralesional triamcinolone injection impact pain perceptions for participants with keloids or hypertrophic scars? Does topical cryotherapy affect provider-assessed injection resistance compared with standard injection alone? Researchers will split the keloid/hypertrophic scar into two halves. One half will be treated with cryotherapy followed by steroid injection, while the other half will be treated with steroid injection alone to evaluate differences in pain perception and injection resistance. Participants will rate pain after each injection using a 10-point numeric pain scale. Clinicians will rate the resistance after each injection using a 10-point numeric scale.

Official title: Topical Cryotherapy to Reduce Pain During Steroid Injections for Keloid and Hypertrophic Scars: A Pilot Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2026-04

Completion Date

2026-08

Last Updated

2026-04-08

Healthy Volunteers

No

Interventions

DEVICE

Cryotherapy with liquid nitrogen

liquid nitrogen spray (\~10 seconds)

DRUG

Intralesional Triamcinolone 10 mg/ml

Intralesional triamcinolone

Locations (1)

University of Pittsburgh

Pittsburgh, Pennsylvania, United States