Clinical Research Directory
Browse clinical research sites, groups, and studies.
Topical Cryotherapy and Keloid/Hypertrophic Scars
Sponsor: Sonal Choudhary
Summary
The goal of this clinical trial is to determine whether the application of brief topical cryotherapy immediately before intralesional corticosteroid injections can reduce pain and injection resistance during routine treatment of keloid and hypertrophic scars in adult patients. The main questions it aims to answer are: Does topical cryotherapy applied before intralesional triamcinolone injection impact pain perceptions for participants with keloids or hypertrophic scars? Does topical cryotherapy affect provider-assessed injection resistance compared with standard injection alone? Researchers will split the keloid/hypertrophic scar into two halves. One half will be treated with cryotherapy followed by steroid injection, while the other half will be treated with steroid injection alone to evaluate differences in pain perception and injection resistance. Participants will rate pain after each injection using a 10-point numeric pain scale. Clinicians will rate the resistance after each injection using a 10-point numeric scale.
Official title: Topical Cryotherapy to Reduce Pain During Steroid Injections for Keloid and Hypertrophic Scars: A Pilot Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-04
Completion Date
2026-08
Last Updated
2026-04-08
Healthy Volunteers
No
Conditions
Interventions
Cryotherapy with liquid nitrogen
liquid nitrogen spray (\~10 seconds)
Intralesional Triamcinolone 10 mg/ml
Intralesional triamcinolone
Locations (1)
University of Pittsburgh
Pittsburgh, Pennsylvania, United States