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To Check Comparison of Apremilast and Methotrexate Efficacy in Patients With Moderate to Severe Plaque Psoriasis Presented to Tertiary Care Hospital
Sponsor: Syeda Sana Zaman
Summary
This study aims to compare efficacy of methotrexate vs apremilast in the management of chronic plaque psoriasis.Given the high prevalence of psoriasis in Pakistan and the significant psychological impact on patients, particularly in Peshawer,this study will provide valuable insights into optimal treatment strategies.
Official title: Comparison of Efficacy of Methotrexate vs Apremilast in Moderate to Severe Plaque Psoriasis
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
106
Start Date
2025-12-25
Completion Date
2026-06-25
Last Updated
2026-01-13
Healthy Volunteers
Yes
Conditions
Interventions
Methotrexate
Group A will recieve methotrexate 10-25mg once weekly for 3 months. Along with folic acid once daily except on day of methotrexate.
Apremilast
Group B will recieve tablet apremilast 30mg twice daily for 3 months.
Locations (1)
MTI-HMC Peshawar
Peshawar, Khyber Pukhtunkhwa, Pakistan