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A Prospective Multicenter Study of the Association Between TCM Syndromes and EGFR-TKI Efficacy in Lung Cancer Patients
Sponsor: Guangzhou University of Traditional Chinese Medicine
Summary
The goal of this observational study is to learn about the relationship between TCM body constitution patterns (called "syndromes") and the effectiveness of EGFR-TKI targeted drugs in patients with lung cancer. Approximately 3000 patients with EGFR-mutant non-small cell lung cancer who are about to start or are already taking EGFR-TKI drugs as part of their regular medical care will be invited to join. Participants will be followed for up to 5 years. During routine clinic visits, researchers will collect their TCM information (such as tongue images and pulse readings) and store small samples of their blood, stool, and tongue coating for future research.
Official title: A Clinical Study on the Patterns of Traditional Chinese Medicine Syndromes and Efficacy Differences in Lung Cancer Patients Treated With EGFR-TKI
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
3000
Start Date
2026-01
Completion Date
2031-07
Last Updated
2026-01-13
Healthy Volunteers
No
Conditions
Interventions
EGFR-TKI
Standard treatment with EGFR tyrosine kinase inhibitors (e.g., gefitinib, erlotinib, osimertinib) for NSCLC. The study observes its association with TCM syndrome patterns.
Locations (6)
Beijing chest Hospital
Beijing, Beijing Municipality, China
Guang'anmen Hospital of china Academy of chinese Medical Sciences
Beijing, Beijing Municipality, China
Guangdong Provincial Hospital of Traditional Chinese Medicine
Guangzhou, Guangdong, China
Affiliated Hospital of Xinxiang Medical University, Henan province
Weihui, Henan, China
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine
Shanghai, Shanghai Municipality, China
Sichuan Cancer Hospital and Research Institute
Chengdu, Sichuan, China