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Clinical Study of UTAA07 Injection in the Treatment of Hematologic and Lymphatic Systemic Malignancies
Sponsor: PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Summary
This is a single-arm, open-label study designed to evaluate the safety, tolerability and cellular pharmacokinetic profiles of UTAA07 Injection. It also aims to preliminarily assess the efficacy of the investigational drug in subjects with relapsed/refractory hematolymphoid malignancies, so as to identify the optimal dose for subsequent formal clinical trials.
Official title: Clinical Study of UTAA07 Injection in the Treatment of CD7 Positive Adult Relapsed/Refractory Hematologic and Lymphatic Systemic Malignancies
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2025-12-12
Completion Date
2027-12-31
Last Updated
2026-01-14
Healthy Volunteers
No
Conditions
Interventions
CAR-T cell infusion
CAR-T cell infusion
UTAA07 injection
UTAA07 Injection is a chimeric antigen receptor (CAR)-engineered γδ T-cell product that targets the CD7 antigen expressed on the surface of tumor cells.
Locations (1)
The First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China