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RECRUITING
NCT07339319

Treatment and Outcome of Patients With Mild Head Injury

Sponsor: Azienda USL Reggio Emilia - IRCCS

View on ClinicalTrials.gov

Summary

The study aims to assess the incidence of complications, such as intracranial haemorrhages and neurological deficits, in patients with head trauma treated in the emergency departments of the Emilia-Romagna Region and to compare the prognostic accuracy of the Canadian CT Head Rule and NEXUS Head CT Instrument in predicting post-traumatic complications. This is a retrospective multicentre cohort study that includes patients aged 18 years or older with isolated head trauma who underwent brain CT within 24 hours of the trauma. The data, sourced from hospital databases, will include medical history, prognostic scores, instrumental examinations, pharmacotherapy and adverse events. The primary objective is to determine the incidence of complications in patients who require surgery or who die, while the secondary objectives aim to compare the prognostic effectiveness of the two instruments in predicting complications. In addition, the study will examine the management strategies adopted and seek to identify any predictors of complications not included in current prognostic models. The results will contribute to improving the management of head trauma in emergency departments and optimising the use of available prognostic tools.

Official title: Treatment and Outcome of Patients With Mild Head Injury: a Retrospective Multicentre Study in Emilia Romagna

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

4500

Start Date

2024-02-01

Completion Date

2026-12-31

Last Updated

2026-01-16

Healthy Volunteers

No

Locations (4)

Ospedale Maggiore di Bologna

Bologna, Italy

Ospedale Sant'Orsola di Bologna

Bologna, Italy

Ospedale di Ferrara

Modena, Italy

AziendaUSL IRCCS Reggio Emilia

Reggio Emilia, Italy