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Pistachio Snacking and Metabolic Flexibility
Sponsor: University of South Carolina
Summary
The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) in healthy overweight and obese adults. Secondary goals include evaluating effects on changes in diet quality, sleep characteristics, physical activity, and hormonal health in women. In randomized order, participants will complete four days of pistachio snacking and four days of normal dietary habits (control). For both conditions, primary outcomes of resting substrate metabolism, metabolic flexibility during exercise, and post-exercise substrate metabolism will be measured pre-post intervention via indirect calorimetry. Secondary outcome of diet quality (kcal, carb, fat, protein) will be measured pre-post intervention via diet log. Exploratory outcomes of daily physical activity (steps, intensity), nightly sleep characteristics (quantity, quality, latency, efficiency), and daytime sleepiness and hunger.
Official title: Effects of Pistachio Snacking on Metabolic Flexibility in Healthy Overweight and Obese Adults
Key Details
Gender
All
Age Range
25 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-09-01
Completion Date
2026-12-31
Last Updated
2026-01-14
Healthy Volunteers
Yes
Conditions
Interventions
Pistachio
Roasted, lightly salted, pistachio kernels (no shell)
Locations (1)
Public Health Research Center: Clinical Exercise Research Center
Columbia, South Carolina, United States