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ACTIVE NOT RECRUITING
NCT07341113

Positional Effects on Lung Ventilation and Perfusion in Obesity

Sponsor: Koç University

View on ClinicalTrials.gov

Summary

Electrical Impedance Tomography (EIT) is a non-invasive, bedside monitoring tool that provides real-time information on regional ventilation and perfusion. In particular, EIT has the potential to guide individualized mechanical ventilation in obese patients by revealing how gravitational and positional factors alter regional lung behavior. Assessing the effects of different horizontal positions on both ventilation and perfusion may help optimize respiratory management strategies tailored to body habitus. By comparing obese and non-obese healthy participants across different positions, this study aims to provide novel insights into the postural effects on lung aeration and perfusion distribution, and to highlight the role of EIT in tailoring individualized ventilation strategies.

Official title: Effects of Body Position on Ventilation and Perfusion Distribution in Obese and Non-Obese Healthy Volunteers Assessed by Electrical Impedance Tomography

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

OBSERVATIONAL

Enrollment

40

Start Date

2025-12-01

Completion Date

2026-01-31

Last Updated

2026-01-20

Healthy Volunteers

Yes

Interventions

OTHER

Standardized body positioning

Standardized changes in body position (supine, Trendelenburg, prone, and lateral positions) performed solely for physiologic assessment of ventilation and perfusion using electrical impedance tomography. This does not constitute a therapeutic or preventive intervention.

Locations (1)

Koç University Hospital

Istanbul, Turkey (Türkiye)