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Worldwide Assessment of Deceased Donor Kidney Utilization
Sponsor: Paris Translational Research Center for Organ Transplantation
Summary
The persistent imbalance between kidney transplant demand and organ availability remains a major global challenge. Optimizing the utilization of kidneys from deceased donors is a critical strategy to expand the donor pool and increase access to transplantation. Previous studies have demonstrated substantial international differences in kidney acceptance and discard practices, with significant potential gains in allograft life-years through optimized utilization. However, major changes in allocation policies, donor characteristics, preservation technologies, and global events such as the COVID-19 pandemic may have altered contemporary utilization patterns. This study aims to characterize international trends in deceased donor kidney utilization, compare allograft survival across countries, and estimate potential transplantable allograft life-years gained through improved utilization practices.
Official title: Worldwide Assessment of Deceased Donor Kidney Utilization: Disparities, Temporal Trends, and Outcomes
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
300000
Start Date
2025-11-01
Completion Date
2026-11
Last Updated
2026-01-14
Healthy Volunteers
No
Locations (2)
Vanderbilt Center for Transplant Science, Vanderbilt University Medical Center, Nashville, TN, USA
Nashville, Tennessee, United States
Paris Institute for Transplantation and Organ Regeneration, INSERM, UMR-S970, Paris, France
Paris, France