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Long-term Adaptations of Skeletal Muscle After Hybrid Training.
Sponsor: University of Thessaly
Summary
Obesity is a major challenge for public health and renders it imperative to reduce its prevalence. High intensity interval training (HIIT) is a form of exercise training that can efficiently induce weight loss in adults with overweight or obesity, even in the absence of dietary intake manipulation. Hybrid type training represents a form of HIIT, that incorporates both cardiorespiratory and musculoskeletal stimuli, by combining multiple types of exercise into a circuit-type, interval style workout. Recent evidence suggests that long-term participation in hybrid HIIT results in significant health-related benefits. However, the molecular mechanisms driving the chronic effects of hybrid HIIT on cardiometabolic and musculoskeletal health remains to be elucidated.
Official title: Long-term Adaptations of Skeletal Muscle in Overweight and Obese Individuals After Hybrid Training.
Key Details
Gender
All
Age Range
30 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-01-08
Completion Date
2026-12-20
Last Updated
2026-01-14
Healthy Volunteers
Yes
Conditions
Interventions
Exercise training
Participants will perform a six-month hybrid training program while receiving a balanced diet. The periodization of hybrid training intervention will consist of three 2-month phases of gradually increased exercise intensity and volume. In every training will participate 5-8 individuals. The training will contain 6-12 different exercises (stations), depending on the phase of the intervention, which will be executed in a circuit for a total of 2-3 rounds, with 2-3 minutes of rest period between sets (depending on the phase). The exercise execution will last 20-45 seconds, and the rest between them will last 30-60 seconds (depending on the phase), while the exercise intensity will range from 75 to 85% of maximal heart rate. The stations of hybrid training will contain multi-joint exercises or neuromuscular activation exercises using either body weight resistance or portable equipment.
Control group
Participants will receive a balanced diet but will not participate in any type of exercise training over a six month period.
Locations (1)
Department of Physical Education and Sport Science Trikala, University of Thessaly
Trikala, Thessaly, Greece