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ENROLLING BY INVITATION
NCT07341841
NA

Assessing Obesity Related Risk Factors in Adult Population: A Genetic and Behavioral Study

Sponsor: Augusta University

View on ClinicalTrials.gov

Summary

This study aims to explore the association between Melanocortin-4 Receptor (MC4R) polymorphisms, eating habits, and social determinants of health in a heterogeneous adult population in Georgia, USA.

Official title: Assessing Obesity Related Risk Factors in Burke, Columbia, Richmond (BCR) Adult Population: A Genetic and Behavioral Study

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2026-01-01

Completion Date

2026-12-01

Last Updated

2026-01-14

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

Diet and exercise

Diet intervention: Participants will be randomly divided into a control group (n=50) and a training group (n=50) using the simplest method of assigning participants to different treatment groups: a coin toss. They will be surveyed using the modified DHII questionnaire to assess their caloric intake. The baseline calorie intake will be evaluated during the first visit. Participants will be instructed to reduce their portion sizes by half of what they typically consume. The commitment of participants will be for 8 weeks. Exercise intervention: In the first visit, subjects will be familiarized with exercise on a bicycle ergometer to eliminate the novel effects of a new experience. The subjects in the training group will then come to our laboratory to participate in an 8-week exercise program; the control group will not undergo training during this experimental period. The training group will train on a bicycle ergometer for 30 minutes, 3 days a week, for 8 weeks.

BEHAVIORAL

Lifestyle Intervention

8-week personalized diet using a personalized low-calorie diet based on the caloric intake baseline using modified Diet History Questionnaire II (DHQ II)

BEHAVIORAL

Exercise

8-week personalized physical activity- subjects will be doing 30-minute exercise three times a week using a bicycle ergometer

Locations (1)

Augusta University

Augusta, Georgia, United States