Clinical Research Directory

Inclusion Criteria: * Inclusion Criteria: * history of Chronic Constipation (CC), as defined by either experiencing two or fewer Complete Spontaneous Bowel Movements (CSBMs) per week for a minimum of 6 consecutive months before the screening visit * Reporting a sensation of incomplete evacuation or straining during at least a quarter of their bowel movements (according to the generally accepted definition of constipation). * Patients must have had CC persisting for more than 6 months, failed to respond to or be intolerant of medical treatment for at least 3 months Inclusion Criteria (for group B): Not having functional constipation Exclusion Criteria: * \- pregnant or lactating women * Chronic Constipation (CC) resulting from anorectal malformations such as colorectal or anal organic lesions, pelvic floor disorders requiring surgical intervention as determined by the investigator (such as rectal prolapse, rectocele, or enterocele) * presence of implanted electronic devices like cardiac pacemakers, defibrillators, cardiac pumps, or spinal stimulators * CC attributable to medications or neurologic, endocrine, or metabolic conditions * prior history of partial colectomy; conditions like megacolon, megarectum, or colonic inertia * skin abnormalities that hinder the placement of electrodes * women lacking adequate contraception (hormonal or intrauterine device).