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Adaptive Stereotactic Radiotherapy for Localized Prostate Cancer
Sponsor: Clinique Sainte Clotilde
Summary
This study evaluates whether adaptive stereotactic body radiotherapy (SBRT) provides dosimetric advantages compared to non-adaptive SBRT in localized prostate cancer. Five low-dose CT scans are performed before each SBRT session to assess anatomical variations (bladder filling, rectal volume) and determine if a dosimetric recalculation would have been required. The study also evaluates cumulative dose to organs at risk, patient-reported quality of life over 24 months, and overall and recurrence-free survival.
Official title: Intérêt de la radiothérapie Adaptative en stéréotaxie Prostatique
Key Details
Gender
MALE
Age Range
60 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-11-18
Completion Date
2029-05-01
Last Updated
2026-01-15
Healthy Volunteers
No
Conditions
Interventions
Low-dose CT imaging before each SBRT session
Five low-dose, non-contrast CT scans performed immediately before each SBRT session (≈10 min before treatment) to assess anatomical variations impacting target volume and organ-at-risk dosimetry.
Locations (1)
Clinique Sainte Clotilde
Saint-Denis, Reunion