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Prevention of Surgical Site Infection in Open Paediatric Groin Surgeries Using Intravenous Prophylactic Antibiotics and Antimicrobial-coated Sutures
Sponsor: Olawumi Olajide
Summary
The goal of this clinical trial is to learn if the use of prophylactic antibiotics and antimicrobial-coated sutures can prevent surgical site infection in children undergoing open groin surgeries. The main question it aims to answer is: • Does the use of intravenous prophylactic antibiotics or antimicrobial-coated sutures significantly reduce the occurrence of surgical site infection in children undergoing open groin surgeries? Researchers will compare no antibiotic use to the use of intravenous prophylactic antibiotics, or antimicrobial-coated sutures to see if the use of intravenous prophylactic antibiotics and antimicrobial-coated sutures significantly reduces the occurrence of surgical site infection following open groin surgeries in children. Participants will: * Undergo open groin surgery with either the use of intravenous prophylactic antibiotic or antimicrobial-coated sutures or without antibiotic use * Visit the clinic on postoperative days 5, 13 and 30 for review of the surgical wounds for any sign of infection.
Official title: Intravenous Prophylactic Antibiotics and Antimicrobial-Coated Sutures in Preventing Surgical Site Infection in Open Paediatric Groin Surgeries: A 3-arm Randomized Controlled Trial
Key Details
Gender
All
Age Range
Any - 15 Years
Study Type
INTERVENTIONAL
Enrollment
174
Start Date
2025-03-09
Completion Date
2026-02-27
Last Updated
2026-01-16
Healthy Volunteers
No
Interventions
Antimicrobial-coated sutures
Use of Antimicrobial-coated sutures to close all layers of the surgical wound following open paediatric groin surgery
Intravenous Cefuroxime
Intravenous cefuroxime is given at the induction of anaesthesia
Placebo intravenous injection
0.2ml of Vitamin Bco injection + 9.8ml sterile water
Locations (1)
Obafemi Awolowo University Teaching Hospitals Complex
Ile-Ife, Osun State, Nigeria