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RECRUITING
NCT07346742
NA

Prevention of Surgical Site Infection in Open Paediatric Groin Surgeries Using Intravenous Prophylactic Antibiotics and Antimicrobial-coated Sutures

Sponsor: Olawumi Olajide

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if the use of prophylactic antibiotics and antimicrobial-coated sutures can prevent surgical site infection in children undergoing open groin surgeries. The main question it aims to answer is: • Does the use of intravenous prophylactic antibiotics or antimicrobial-coated sutures significantly reduce the occurrence of surgical site infection in children undergoing open groin surgeries? Researchers will compare no antibiotic use to the use of intravenous prophylactic antibiotics, or antimicrobial-coated sutures to see if the use of intravenous prophylactic antibiotics and antimicrobial-coated sutures significantly reduces the occurrence of surgical site infection following open groin surgeries in children. Participants will: * Undergo open groin surgery with either the use of intravenous prophylactic antibiotic or antimicrobial-coated sutures or without antibiotic use * Visit the clinic on postoperative days 5, 13 and 30 for review of the surgical wounds for any sign of infection.

Official title: Intravenous Prophylactic Antibiotics and Antimicrobial-Coated Sutures in Preventing Surgical Site Infection in Open Paediatric Groin Surgeries: A 3-arm Randomized Controlled Trial

Key Details

Gender

All

Age Range

Any - 15 Years

Study Type

INTERVENTIONAL

Enrollment

174

Start Date

2025-03-09

Completion Date

2026-02-27

Last Updated

2026-01-16

Healthy Volunteers

No

Interventions

DEVICE

Antimicrobial-coated sutures

Use of Antimicrobial-coated sutures to close all layers of the surgical wound following open paediatric groin surgery

DRUG

Intravenous Cefuroxime

Intravenous cefuroxime is given at the induction of anaesthesia

OTHER

Placebo intravenous injection

0.2ml of Vitamin Bco injection + 9.8ml sterile water

Locations (1)

Obafemi Awolowo University Teaching Hospitals Complex

Ile-Ife, Osun State, Nigeria