Clinical Research Directory

Inclusion Criteria: 1. Have place of residence in a municipality where the pilot vaccination strategy is implemented; 2. Are in an eligible age-group to receive the VLA1553 vaccine; 3. Have been notified in SINAN as a suspected case for CHIK or Dengue surveillance during the study period; 4. Have a sample registered in GAL that is collected within 0-5 days following the onset of CHIKV-like symptoms and is tested for CHIKV using RT-PCR; 5. Have complete data in the Brazilian MoH databases (SINAN and GAL) on age, sex, municipality of residence, sample collection date, and date of symptom onset and the healthcare facilities where the suspected case was reported. Exclusion Criteria: 1. Have inconclusive RT-PCR result for CHIKV; 2. Have the first CHIKV-like symptom onset less than 14 days from date of vaccination.