Clinical Research Directory

Inclusion Criteria: * Age ≥ 18 years (adults capable of giving consent) * Capacity to consent. The subjects are able to understand the information provided and give their written consent. * Belonging to one of the following cohorts: * Endurance athletes: at least 3× per week ≥ 60 minutes of intensive endurance training (e.g., running, cycling, swimming) * Strength athletes: at least 3× per week ≥ 60 minutes of intensive strength training without additional endurance training * Healthy control subjects: less than 2× per week \< 30 minutes of physical activity, no known vascular diseases * PAD patients: diagnosed peripheral arterial occlusive disease in Fontaine stage I or IIa Women of childbearing age with or without contraception may participate, as there are no risks of harm to the fetus. * Consent to pseudonymized data collection and storage in accordance with the GDPR. Exclusion Criteria: * Age over 75 years * Minors (Age \< 18) * safety concerns on the part of the study physician, e.g., in the case of of: physical, mental or psychiatric illnesses, acute or chronic conditions that could jeopardise safety or data quality * Taking medications that could affect physical performance or physiological measurements (e.g., heart rate, oxygen uptake). * Pregnancy with known risks or complications (participation is possible in principle, but subject to individual medical review). * Refusal to participate or lack of informed consent.