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RECRUITING
NCT07347925

Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF

Sponsor: Future University in Egypt

View on ClinicalTrials.gov

Summary

This study looks at people with heart failure who are admitted to the hospital. The goal of the study is to understand whether taking a heart failure medicine called angiotensin receptor-neprilysin inhibitor (ARNI) before hospital admission affects short-term health outcomes. The study will compare two groups of participants: those who were already taking ARNI before coming to the hospital and those who were not. Information will be collected from medical records during the hospital stay, including heart-related events, kidney-related events, and how long participants stay in the hospital. Some participants will also be followed for a short period after discharge. This study may help improve understanding of outcomes associated with ARNI use in people with heart failure in routine clinical care.

Official title: Evaluating the Impact of Pre-Hospital Angiotensin Receptor-Neprilysin Inhibitor (ARNI) Therapy on Short-Term Clinical Outcomes in Heart Failure Patients With Reduced Ejection Fraction: A Comparative Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

140

Start Date

2026-01-10

Completion Date

2026-05-01

Last Updated

2026-01-16

Healthy Volunteers

No

Conditions

Interventions

OTHER

Prehospital ARNI use

Participants who were using ARNI therapy before hospital admission

OTHER

No prehospital ARNI use

Participants who were not using ARNI therapy before hospital admission

Locations (1)

Mansoura university Hospital

Al Mansurah, Egypt