Clinical Research Directory

Inclusion Criteria: 1. Age range: 18-80 years old. 2. Electively undergo minimally invasive (thoracoscopic or robotic) surgery for the treatment of lung cancer 3. Is willing and capable of providing consent. Exclusion Criteria: 1. Palliative surgery without intention of cure. 2. Extensive comorbidities (ASA IV). 3. Patients with known or suspected allergy to lidocaine. 4. Patients who are currently pregnant or breastfeeding. 5. Patients who may experience adverse reactions due to accumulation of lidocaine during intravenous infusion, as stated in the Summary of Product Characteristics (SmPC) for lidocaine. 6. Currently, there is abnormal liver function, with ALT or AST levels exceeding the laboratory reference range by a factor of 2. 7. Currently, there is severe renal insufficiency (serum creatinine ≥451umol/L or glomerular filtration rate (calculated using the MDRD formula) \<30ml/min). 8. Epilepsy. 9. Patients with cardiac conduction abnormalities, including second-degree or third-degree heart block without a pacemaker, left bundle branch block, sick sinus syndrome, and pre-excitation syndrome (confirmed by medical history and electrocardiogram), as well as those with low cardiac output due to reduced left ventricular ejection fraction. 10. Concurrent use with continuous infusion of other local anesthetic drugs (such as epidural). 11. Patients who use drugs that may cause reasons for exclusion, including Class I and Class III antiarrhythmic drugs (such as mexiletine and amiodarone), cimetidine, and antiviral drugs. Eligibility will be determined by local clinicians and verified by clinical trial doctors. 12. Patients with body weight \<40kg