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NOT YET RECRUITING
NCT07348003
NA

Examining the Effectiveness of Single-Limb Exercise Training for COPD Patients During Exacerbation Periods

Sponsor: Alper Kemal Gürbüz

View on ClinicalTrials.gov

Summary

Resistance exercise applications during acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) are employed to enhance functional capacity and prevent muscle atrophy by increasing muscle strength. Owing to the limited cardiorespiratory reserve of COPD patients, single-limb exercises are better tolerated compared to traditional bilateral exercises. A study conducted by Vogiatzis et al. (2009) indicated that single-leg exercises require lower ventilation and result in more efficient oxygen consumption than bilateral exercises. This physiological advantage may be effective in reducing muscle weakness by increasing exercise endurance in COPD patients with restricted respiratory capacity. The present study aims to demonstrate that single-limb resistance exercise is an effective rehabilitation method for increasing functional exercise capacity in patients during COPD exacerbations compared to a control group. Furthermore, the therapeutic effects of single-limb resistance exercises on dyspnea perception, fatigue, anxiety, and depression will be established. The study will also show that these exercises are both feasible and safe within rehabilitation protocols during the exacerbation period.

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2026-03-02

Completion Date

2027-09-25

Last Updated

2026-01-16

Healthy Volunteers

No

Interventions

OTHER

Single Limb Exercise Training

Participants will perform unilateral resistance exercises for six major muscle groups (shoulder flex/abd, elbow flex, hip flex, knee flex/ext) using free weights in a seated position. The intensity is set at 50-70% of 1RM, consisting of 2 sets of 8 repetitions per limb. This 8-week program will be conducted twice weekly as an adjunct to routine hospital physiotherapy and standard inpatient physiotherapy, including breathing retraining (diaphragmatic and pursed-lip breathing) and thoracic expansion exercises.

OTHER

Routine Exercise

Physiotherapy Intervention: Just standard inpatient physiotherapy, including breathing retraining (diaphragmatic and pursed-lip breathing) and thoracic expansion exercises.

Locations (1)

Alper Kemal Gürbüz

Ankara, Ankara, Turkey (Türkiye)