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RECRUITING
NCT07348757

rFSH vs rFSH+rLH in Dydrogesterone-Based Progestin Protocol: A Prospective Study

Sponsor: Centrum Clinic IVF Center

View on ClinicalTrials.gov

Summary

This study aims to compare two commonly used hormone treatments for women undergoing IVF. All participants will receive a stimulation protocol that includes dydrogesterone, a medication used to safely control natural hormone surges during treatment. The study will observe women who are treated either with recombinant FSH alone or with a combination of recombinant FSH and recombinant LH-both routinely used options in our clinic. Investigators will prospectively monitor how these treatments affect the growth of ovarian follicles, the number of mature eggs collected, the quality of developing embryos, and early pregnancy outcomes. No additional procedures or medications will be required beyond standard IVF care. The goal is to better understand whether adding recombinant LH provides any measurable benefit in dydrogesterone-based PPOS cycles.

Official title: Comparison of rFSH Alone Versus rFSH+rLH in Dydrogesterone-Based Progestin Protocol Cycles

Key Details

Gender

FEMALE

Age Range

18 Years - 43 Years

Study Type

OBSERVATIONAL

Enrollment

300

Start Date

2026-01-05

Completion Date

2026-05-10

Last Updated

2026-02-03

Healthy Volunteers

Yes

Locations (2)

Centrum Clinic IVF Center

Ankara, Ankara, Turkey (Türkiye)

Bahçeci IVF Center

Ankara, Turkey (Türkiye)