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Cold Plasma Effects on Dental Implant Stability
Sponsor: Kahramanmaras Sutcu Imam University
Summary
Cold plasma-mediated implant surface activation may reverse the biological aging of titanium by enhancing hydrophilicity and cellular response. The aim of this study was to clinically compare the effects of three different cold plasma systems on the stability of dental implants. In this prospective randomized controlled within-patient trial, a total of 44 implants were placed in 11 patients. In each patient, four implants were randomly allocated to one of the following groups: control, vacuum plasma, argon jet plasma, and cold atmospheric plasma. All implants were placed using a single-stage protocol with a minimum insertion torque of 45 Ncm. Implant stability was assessed using resonance frequency analysis (ISQ values) immediately after placement and at 2, 4, and 8 weeks.
Official title: Clinical Evaluation of Cold Plasma Surface Activation Using Different Plasma Systems on Early Implant Stability: A Randomized Controlled Within-Patient Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
11
Start Date
2025-02-24
Completion Date
2025-09-09
Last Updated
2026-05-11
Healthy Volunteers
No
Conditions
Interventions
Dental implant placement
The dental implant was placed without any plasma application.
Dental implant placement and vacuum plasma application
The dental implant was placed with non-thermal low-pressure cold plasma application
Dental implant placement and argon jet plasma application
The dental implant was placed with argon jet plasma application
Dental implant placement and cold atmospheric plasma application
The dental implant was placed with cold atmospheric plasma application
Locations (1)
Kahramanmaras Sutcu Imam University, Faculty of Dentistry
Kahramanmaraş, Turkey (Türkiye)