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NOT YET RECRUITING
NCT07350512
NA

Investigating the Acute Effects of Increasing Alanine Exposure in Healthy Participants

Sponsor: Nicolai Jacob Wewer Albrechtsen

View on ClinicalTrials.gov

Summary

In this study the investigators will investigate the acute effects of increasing alanine exposure on metabolic parameters in healthy participants. Participants will participate in one study day. After initial baseline blood samples, a three-hour intravenous infusion with glucagon will be initiated. The infusion rate will be increased every 30 minutes.

Official title: Investigating the Effect of Glucagon on Cognitive Function and Cerebral Glucose Metabolism in Humans: A Pilot Study

Key Details

Gender

All

Age Range

25 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

15

Start Date

2026-01-20

Completion Date

2027-01-20

Last Updated

2026-01-20

Healthy Volunteers

Yes

Interventions

OTHER

alanine

A three-hour intravenous infusion with alanine with increasing infusion rate (from 1.4 μmol/kg/min and to 28 μmol/kg/min)

Locations (1)

Department of Clinical Biochemistry, Copenhagen University Hospital - Bispebjerg and Frederiksberg

Copenhagen, Denmark