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Investigating the Acute Effects of Increasing Alanine Exposure in Healthy Participants
Sponsor: Nicolai Jacob Wewer Albrechtsen
Summary
In this study the investigators will investigate the acute effects of increasing alanine exposure on metabolic parameters in healthy participants. Participants will participate in one study day. After initial baseline blood samples, a three-hour intravenous infusion with glucagon will be initiated. The infusion rate will be increased every 30 minutes.
Official title: Investigating the Effect of Glucagon on Cognitive Function and Cerebral Glucose Metabolism in Humans: A Pilot Study
Key Details
Gender
All
Age Range
25 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2026-01-20
Completion Date
2027-01-20
Last Updated
2026-01-20
Healthy Volunteers
Yes
Conditions
Interventions
alanine
A three-hour intravenous infusion with alanine with increasing infusion rate (from 1.4 μmol/kg/min and to 28 μmol/kg/min)
Locations (1)
Department of Clinical Biochemistry, Copenhagen University Hospital - Bispebjerg and Frederiksberg
Copenhagen, Denmark