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Clinical Study on a Novel Strategy of Individualized Non-Invasive Neuromodulation for the Treatment of Tic Disorders in Children
Sponsor: Shanghai Children's Medical Center
Summary
This study aims to establish a novel personalized closed-loop NiBS/TMS therapeutic strategy and clinical protocol for children with Tic Disorders (TDs) through a series of scientific investigations. Additionally, it seeks to elucidate the underlying neural circuit mechanisms, enhance the therapeutic efficacy of TMS in pediatric TDs, and achieve precision neuromodulation for children with TDs.
Key Details
Gender
All
Age Range
5 Months - 18 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-06-01
Completion Date
2026-05-31
Last Updated
2026-01-20
Healthy Volunteers
No
Conditions
Interventions
Transcranial Magnetic Stimulation
Transcranial magnetic stimulation (TMS) will be administered to the child using a ZL-N-010 model device, targeting predefined sites in the prefrontal, bilateral temporal, and parietal lobes.
general behavioral therapy
Behavioral interventions include avoiding screen time, parental avoidance of scolding or corporal punishment, and steering clear of activities or emotional stimuli that may exacerbate symptoms.
Locations (1)
Shanghai Children's Medical Center，School of Medicine, Shanghai Jiao Tong University
Shanghai, Shanghai Municipality, China