Clinical Research Directory
Browse clinical research sites, groups, and studies.
Topical Diacerein in Psoriasis Vulgaris
Sponsor: Cairo University
Summary
The goal of this clinical trial is to evaluate the safety and effectiveness of topical diacerein in adults with psoriasis vulgaris. The primary objective of the study is to compare the proportion of participants who achieve a clinically meaningful improvement in disease severity between the topical diacerein group and the placebo group. Participants will: Be assigned to receive topical diacerein 1% or placebo twice daily for a treatment period of 2 months. Attend follow-up visits at Weeks 2, 4, 6, and 8. Undergo an additional evaluation one month after treatment cessation.
Official title: The Efficacy of Topical Diacerein Cream in Patients With Psoriasis Vulgaris
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-02-01
Completion Date
2027-05-01
Last Updated
2026-01-20
Healthy Volunteers
No
Conditions
Interventions
Diacerein
Topical diacerein cream 1% will be applied to affected skin areas twice daily for a treatment duration of two months.
Placebo
A matching placebo topical formulation will be applied to affected skin areas twice daily for a treatment duration of two months.
Locations (1)
Kasr Al-Ainy Psoriasis Unit
Cairo, Egypt