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The Application of T1 Mapping in Real-World
Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital
Summary
The goal of this observational study is to create a comprehensive real-world spectrum of T1 mapping measurements across different heart conditions. We aim to establish reference values for how heart tissue characteristics vary in various diseases, which will help doctors better interpret these advanced MRI measurements in clinical practice. The main questions it aims to answer are: What are the normal T1 mapping values for different heart diseases, and how do they compare to healthy hearts? Can we use the simpler "native T1" measurement (without contrast dye) instead of the more complex "ECV" measurement (which requires contrast dye) for diagnosis? Patients with various myocardial conditions will undergo CMR T1 mapping scans. We will analyze the MRI images and clinical records to establish disease-specific reference ranges for T1 mapping parameters, and validate the diagnostic accuracy of T1 mapping
Official title: The Landscape of T1 Mapping for Disease Profiling in a Real-World Cohort
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
2000
Start Date
2020-03-01
Completion Date
2026-12-01
Last Updated
2026-01-21
Healthy Volunteers
Yes
Conditions
Interventions
Magnetic Resonance Imaging with Contrast
Participants in this arm undergo a single, standardized cardiac MRI scan with gadolinium-based contrast agent.
Locations (1)
Fuwai Hospital, Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China