Clinical Research Directory
Browse clinical research sites, groups, and studies.
Prognostic Nutritional Index for Predicting Outcomes Following Coronary Artery Bypass Grafting (CABG) Surgery
Sponsor: Benha University
Summary
Coronary artery bypass grafting (CABG) is a major cardiac surgery associated with risks of serious perioperative complications and mortality. Malnutrition and inflammation are known independent risk factors for poor outcomes in patients with coronary artery disease. This retrospective observational study evaluates the Prognostic Nutritional Index (PNI)-a simple score derived from serum albumin and lymphocyte counts-as an objective measure of nutritional and inflammatory status. The research aims to determine how well preoperative PNI and its postoperative changes can predict complications such as acute kidney injury, myocardial infarction, and sternal wound infections in patients undergoing CABG.
Official title: The Merits of the Prognostic Nutritional Index for Prediction of the Outcome of Coronary Artery Bypass Grafting Surgery: A Retrospective Observational Study
Key Details
Gender
All
Age Range
25 Years - 55 Years
Study Type
OBSERVATIONAL
Enrollment
117
Start Date
2025-11-15
Completion Date
2026-01-20
Last Updated
2026-01-21
Healthy Volunteers
No
Conditions
Interventions
Prognostic Nutritional Index (PNI)
Calculated using serum albumin (g/L) and total peripheral lymphocyte count.
Neutrophil-to-Lymphocyte Ratio (NLR)
Calculated from peripheral blood counts.
Body Mass Index (BMI)
Calculated from preoperative weight and height.
Locations (1)
Benha University
Banhā, Al Qalyoubia, Egypt