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Impact of Different Cardioplegia Solutions on Indicators of Myocardial Injury During Coronary Surgery
Sponsor: Damascus University
Summary
The aim of the present study is to investigate intra-operative changes in markers of myocardial injury during ischemia and reperfusion, comparing three methods of myocardial protection; St. Thomas' cold crystalloid cardioplegia, Calafiore warm blood cardioplegia, or modified del Nido cold blood cardioplegia in routine coronary artery bypass grafting procedures.
Official title: Impact of Different Cardioplegia Solutions on Extracellular Vesicles-derived miRNAs, Complement System, and Neutrophil Extracellular Traps (NETs) as Indicators of Myocardial Injury During Coronary Artery Bypass Surgery
Key Details
Gender
All
Age Range
40 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-02
Completion Date
2027-02
Last Updated
2026-01-22
Healthy Volunteers
No
Interventions
The intervention is the use of a specific cardioplegia solution for myocardial protection
Three different solutions will be used for myocardial protection in this study, and will be compared using markers of myocardial injury
Locations (1)
Damascus University Cardiac Surgery Hospital
Damascus, Rif-dimashq Governorate, Syria