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RECRUITING
NCT07363421
NA

TMS-Induced LH Response in Healthy Women in Luteal Phase

Sponsor: The City College of New York

View on ClinicalTrials.gov

Summary

The purpose of this research is to establish whether non-invasive Transcranial Magnetic Stimulation (TMS), can affect modulation of hormones such: Luteinizing Hormone (LH) and Follicle-stimulating hormone (FSH). The hypothesis is that applying TMS to the Dorsolateral Prefrontal Cortex with specific pulse patterns, mimicking endogenous Gonodotropin-Releasing Hormone (GnRH) pulses that are known to stimulate LH secretion may modulate hormonal levels.

Official title: Feasibility Study Protocol: TMS-Induced LH Response in Healthy Women in the Luteal Phase

Key Details

Gender

FEMALE

Age Range

22 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2026-02-24

Completion Date

2026-06-01

Last Updated

2026-03-02

Healthy Volunteers

Yes

Conditions

Interventions

DEVICE

Transcranial Magnetic Stimulation Active

Participants will receive stimulation to the left DLPFC. Stimulation intensity will be standardized based on resting motor threshold. Stimulation will be delivered using NeuroStar system.

DEVICE

Transcranial Magnetic Stimulation Sham

Participants will undergo identical procedure to the active TMS group, including coil placement, session duration, and acoustic and somatic sensations. A sham device setting will be used that mimics the sound but does not deliver an effective magnetic field to the DLPFC.

Locations (1)

Site 1

New York, New York, United States