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TMS-Induced LH Response in Healthy Women in Luteal Phase
Sponsor: The City College of New York
Summary
The purpose of this research is to establish whether non-invasive Transcranial Magnetic Stimulation (TMS), can affect modulation of hormones such: Luteinizing Hormone (LH) and Follicle-stimulating hormone (FSH). The hypothesis is that applying TMS to the Dorsolateral Prefrontal Cortex with specific pulse patterns, mimicking endogenous Gonodotropin-Releasing Hormone (GnRH) pulses that are known to stimulate LH secretion may modulate hormonal levels.
Official title: Feasibility Study Protocol: TMS-Induced LH Response in Healthy Women in the Luteal Phase
Key Details
Gender
FEMALE
Age Range
22 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2026-02-24
Completion Date
2026-06-01
Last Updated
2026-03-02
Healthy Volunteers
Yes
Conditions
Interventions
Transcranial Magnetic Stimulation Active
Participants will receive stimulation to the left DLPFC. Stimulation intensity will be standardized based on resting motor threshold. Stimulation will be delivered using NeuroStar system.
Transcranial Magnetic Stimulation Sham
Participants will undergo identical procedure to the active TMS group, including coil placement, session duration, and acoustic and somatic sensations. A sham device setting will be used that mimics the sound but does not deliver an effective magnetic field to the DLPFC.
Locations (1)
Site 1
New York, New York, United States