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Autologous Transplantation of Human Cryopreserved Testis Tissue
Sponsor: Herlev and Gentofte Hospital
Summary
For pre-pubertal boys undergoing gonadotoxic therapies, freezing immature testicular tissue (ITT) containing spermatogonial stem cells (SSCs) is currently the only option to potentially preserve future fertility. This experimental clinical study aims to provide proof-of-concept that frozen-thawed, ectopically autotransplanted adult human testicular tissue can support spermatogenesis in healthy adult men.
Official title: Restoration of Spermatogenesis by Autologous Grafting of Cryopreserved Testis Tissue From Men With Non-Obstructive Azoospermia and Healthy Men With Proven Fertility
Key Details
Gender
MALE
Age Range
40 Years - Any
Study Type
INTERVENTIONAL
Enrollment
5
Start Date
2024-11-04
Completion Date
2027-03
Last Updated
2026-01-23
Healthy Volunteers
Yes
Interventions
Autologous Transplantation of Testis Tissue
Autologous transplantation of testis tissue under the scrotal skin
Locations (1)
Copenhagen University Hospital - Herlev and Gentofte
Herlev, Capital Region, Denmark