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ACTIVE NOT RECRUITING
NCT07364409
NA

Autologous Transplantation of Human Cryopreserved Testis Tissue

Sponsor: Herlev and Gentofte Hospital

View on ClinicalTrials.gov

Summary

For pre-pubertal boys undergoing gonadotoxic therapies, freezing immature testicular tissue (ITT) containing spermatogonial stem cells (SSCs) is currently the only option to potentially preserve future fertility. This experimental clinical study aims to provide proof-of-concept that frozen-thawed, ectopically autotransplanted adult human testicular tissue can support spermatogenesis in healthy adult men.

Official title: Restoration of Spermatogenesis by Autologous Grafting of Cryopreserved Testis Tissue From Men With Non-Obstructive Azoospermia and Healthy Men With Proven Fertility

Key Details

Gender

MALE

Age Range

40 Years - Any

Study Type

INTERVENTIONAL

Enrollment

5

Start Date

2024-11-04

Completion Date

2027-03

Last Updated

2026-01-23

Healthy Volunteers

Yes

Interventions

PROCEDURE

Autologous Transplantation of Testis Tissue

Autologous transplantation of testis tissue under the scrotal skin

Locations (1)

Copenhagen University Hospital - Herlev and Gentofte

Herlev, Capital Region, Denmark