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Pain Assessment in Patients With Idiopathic REM Sleep Behaviour Disorder
Sponsor: University Hospital, Toulouse
Summary
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, with over 12 million patients expected globally by 2040. The disease is currently diagnosed at the appearance of motor symptoms, but by then, over 60% of striatal dopaminergic neurons have already been destroyed. Prodromal symptoms such as idiopathic REM Sleep Behavior Disorder (iRBD), anosmia, mood disorders and constipation appear earlier and are listed as criteria for a prodromal PD diagnosis. Identifying early signs is critical to initiate neuroprotective treatments as early as possible. While pain is prevalent and highly disabling in early PD, no data are currently available on pain perception in iRBD patients, whose condition is of the main risk factor for PD development.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2026-02-01
Completion Date
2026-08-01
Last Updated
2026-03-03
Healthy Volunteers
No
Interventions
Thermo test pain
Patients will undergo a pain test, also called a thermotest, which consists of determining pain thresholds using a thermometer applied to the hand.
Pain questionnaires
Patients will complete various questionnaires about pain
No motors symptoms evaluations
Patients will complete questionnaires
Locations (1)
Centre Expert Parkinson Hôpital Pierre Paul Riquet Place du Docteur Baylac
Toulouse, France