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NCT07366541

Predicting High-Flow Nasal Cannula Failure Using an Electrical Impedance Tomography-Derived Index: A Multicenter Study

Sponsor: Ruijin Hospital

View on ClinicalTrials.gov

Summary

High-Flow Nasal Cannula (HFNC) therapy is widely used to treat acute respiratory failure. However, predicting therapy failure remains challenging as conventional indices rely on intermittent measurements and cannot provide continuous, objective monitoring. Electrical Impedance Tomography (EIT) enables non-invasive, real-time assessment of regional lung ventilation. This study evaluated whether an EIT-derived Flow Index (FI) could predict HFNC therapy failure within 48 hours.

Key Details

Gender

All

Age Range

18 Years - 90 Years

Study Type

OBSERVATIONAL

Enrollment

90

Start Date

2023-12-01

Completion Date

2026-02-01

Last Updated

2026-01-26

Healthy Volunteers

No

Interventions

DEVICE

Electrical impedance tomography(PulmoVista 500, Dräger Medical)

Outcome Parameters: FI, ROX index, respiratory rate, SpO₂

Locations (1)

Department of Critical Care Medicine,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China