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Predicting High-Flow Nasal Cannula Failure Using an Electrical Impedance Tomography-Derived Index: A Multicenter Study
Sponsor: Ruijin Hospital
Summary
High-Flow Nasal Cannula (HFNC) therapy is widely used to treat acute respiratory failure. However, predicting therapy failure remains challenging as conventional indices rely on intermittent measurements and cannot provide continuous, objective monitoring. Electrical Impedance Tomography (EIT) enables non-invasive, real-time assessment of regional lung ventilation. This study evaluated whether an EIT-derived Flow Index (FI) could predict HFNC therapy failure within 48 hours.
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
OBSERVATIONAL
Enrollment
90
Start Date
2023-12-01
Completion Date
2026-02-01
Last Updated
2026-01-26
Healthy Volunteers
No
Conditions
Interventions
Electrical impedance tomography(PulmoVista 500, Dräger Medical)
Outcome Parameters: FI, ROX index, respiratory rate, SpO₂
Locations (1)
Department of Critical Care Medicine,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China