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Clinical and Cost-Effectiveness of Silver Diamine Fluoride and Silver Fluoride, With or Without Application of LED, in Arresting Incipient Permament Molar Caries
Sponsor: Cairo University
Summary
The study aims to compare the effect of international brand ammonia based 38% SDF, water based silver fluoride solution (AgF), an aqueous silver fluoride solution, and local brand ammonia based SDF with and without LED light application on caries arrest of initial enamel pits and fissure caries for permanent teeth of young adults
Official title: Clinical Efficacy and Cost-Effectiveness of Silver Diamine Fluoride and Silver Fluoride to Arrest Incipient Carious Lesions in Permanent Molar Teeth With or Without Application of LED Light: A Randomized Clinical Trial
Key Details
Gender
All
Age Range
18 Years - 25 Years
Study Type
INTERVENTIONAL
Enrollment
366
Start Date
2026-03-01
Completion Date
2027-07-01
Last Updated
2026-01-26
Healthy Volunteers
No
Conditions
Interventions
International Sliver Diamine Fluoride
It is the gold standard; it is an international brand, it is ammonia-based, and it is a remineralizing agent with an application time of 60 seconds.
Local brand Egyptian Silver Diamine Fluoride
It is a new Egyptian brand of SDF; it is ammonia-based, and it is a remineralizing agent with an application time of 60 seconds.
Silver Fluoride
It is a water-based remineralizing agent with an application time of 60 seconds.
International Sliver Diamine Fluoride with LED light
It is an international brand, it is ammonia-based, and it is a remineralizing agent with an application time of 10 seconds, followed by LED light application for 20 seconds.
Local brand Egyptian Silver Diamine Fluoride with LED light
It is a new Egyptian brand of SDF; it is ammonia-based, and it is a remineralizing agent with an application time of 10 seconds, followed by LED application for 20 seconds.
Silver Fluoride with LED light
It is a water-based remineralizing agent with an application time of 10 seconds, followed by LED light application for 20 seconds.