Clinical Research Directory

Inclusion Criteria Patients with acute bilateral partial-thickness (second-degree) thermal burns where both sides/areas are comparable and suitable for intra-patient treatment (one area treated with SSD+HA and the contralateral area with SSD alone) Presentation within 72 hours of burn injury Small to moderate total burn surface area suitable for conservative topical management Burn wounds not requiring immediate excision or grafting at baseline Ability to comply with daily dressing application and follow-up until complete re-epithelialization Written informed consent from patient; for minors, parent/guardian consent and assent where applicable Exclusion Criteria Full-thickness (third-degree) burns or mixed-depth burns in the study areas Chemical, electrical, radiation, or inhalational burns requiring ICU or ventilatory support Infected burn wounds at baseline requiring systemic antibiotics Major comorbidities likely to impair wound healing (e.g., uncontrolled diabetes, severe peripheral vascular disease, immunosuppression, severe malnutrition) Known hypersensitivity to silver sulfadiazine, sulfonamides, hyaluronic acid, or formulation components Pregnancy or lactation (as per institutional policy) Non-comparable bilateral burn wounds Concurrent participation in another interventional wound or burn study