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Zinc Supplementation and Infections in Older Medical Patients
Sponsor: Herlev Hospital
Summary
The goal of this clinical trial is to learn about the effect of zinc supplementation once daily for 12 months in older acute medical patients. The main question it aims to answer is: • Can daily zinc supplementation for 12 months increase Days Alive and Out of Hospital (DAOH)? Researchers will compare zinc supplementation to a control group, a group who do not receive zinc supplementation, to see if zinc supplementation can increase Days Alive and Out of Hospital, reduce antibiotic use, readmissions and mortality. Participants will take 22 mg zinc supplementation once daily for 12 months or not. The researchers will draw data on readmissions, antibiotic use and mortality during the 12 months follow-up period.
Official title: Effect of Zinc Supplementation on Occurrence of Infections in Older Medical Patients (ZOOM) - a Cluster Randomized Controlled Trial (ZOOM OUT).
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
8000
Start Date
2026-02-01
Completion Date
2028-03-15
Last Updated
2026-01-30
Healthy Volunteers
No
Interventions
Zinc (zinc sulphate)
22 mg zinc sulphate tablets taken once daily for 12 months
Locations (1)
Department of Medicine, Copenhagen University Hospital - Herlev and Gentofte
Herlev, Denmark