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ACTIVE NOT RECRUITING
NCT07370753

Early Continuous Renal Replacement Therapy for Pediatric Septic Shock

Sponsor: National Children's Hospital, Vietnam

View on ClinicalTrials.gov

Summary

Septic shock is a major cause of morbidity and mortality in critically ill children. Continuous renal replacement therapy (CRRT) is increasingly used as adjunctive support in pediatric septic shock to improve hemodynamic stability, modulate inflammatory responses, and correct metabolic disturbances. However, evidence regarding optimal indications, timing, and clinical outcomes of early CRRT use in children remains limited. This prospective observational study aims to evaluate associations between early CRRT use and changes in hemodynamics, organ dysfunction, inflammatory cytokine levels, and short-term clinical outcomes in pediatric patients with septic shock admitted to pediatric intensive care units

Official title: Early Application of Continuous Renal Replacement Therapy as Adjunctive Support in Pediatric Septic Shock: A Prospective Observational Study

Key Details

Gender

All

Age Range

1 Month - 17 Years

Study Type

OBSERVATIONAL

Enrollment

50

Start Date

2025-05-20

Completion Date

2028-03-18

Last Updated

2026-01-27

Healthy Volunteers

No

Locations (1)

Vietnam National Children's Hospital

Hanoi, Vietnam