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Allogeneic Adipose Tissue Extract in Wound Treatment and Scar Maturation
Sponsor: Linio Biotech Oy
Summary
This study will evaluate the effect of an allogeneic adipose tissue extract on wound healing and scar maturation. Thirty adult patients scheduled for skin graft surgery will be enrolled. Each patient will have two skin graft donor sites harvested. One skin graft donor site wound will be treated topically with the adipose tissue extract, applied immediately after harvesting and reapplied on Day 3, while the other skin graft donor site wound will receive standard care. The main outcome is the time to complete epithelialization of the wound, as confirmed by investigators and independent reviewers. Secondary measures include wound characteristics, scar formation and scar quality, and monitoring of adverse events, such as wound deterioration.
Official title: The Effect of Allogeneic Human Fat-Derived Extract on Skin Graft Donor Site Wound Healing
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2023-04-11
Completion Date
2026-12-31
Last Updated
2026-01-28
Healthy Volunteers
No
Conditions
Interventions
Topical treatment
The adipose tissue extract will be applied topically to one skin graft donor site wound immediately after harvesting and reapplied on Day 3. The other donor site will receives standard wound care according to hospital protocol, without application of adipose tissue extract. Wounds will be photographed and assessed on Days 3, 7, 14, and 60. Study participants and independent evaluators are blinded to treatment allocation.
Locations (1)
Hospital Nova
Jyväskylä, Finland, Finland