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RECRUITING
NCT07372404
NA

Allogeneic Adipose Tissue Extract in Wound Treatment and Scar Maturation

Sponsor: Linio Biotech Oy

View on ClinicalTrials.gov

Summary

This study will evaluate the effect of an allogeneic adipose tissue extract on wound healing and scar maturation. Thirty adult patients scheduled for skin graft surgery will be enrolled. Each patient will have two skin graft donor sites harvested. One skin graft donor site wound will be treated topically with the adipose tissue extract, applied immediately after harvesting and reapplied on Day 3, while the other skin graft donor site wound will receive standard care. The main outcome is the time to complete epithelialization of the wound, as confirmed by investigators and independent reviewers. Secondary measures include wound characteristics, scar formation and scar quality, and monitoring of adverse events, such as wound deterioration.

Official title: The Effect of Allogeneic Human Fat-Derived Extract on Skin Graft Donor Site Wound Healing

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2023-04-11

Completion Date

2026-12-31

Last Updated

2026-01-28

Healthy Volunteers

No

Conditions

Interventions

PROCEDURE

Topical treatment

The adipose tissue extract will be applied topically to one skin graft donor site wound immediately after harvesting and reapplied on Day 3. The other donor site will receives standard wound care according to hospital protocol, without application of adipose tissue extract. Wounds will be photographed and assessed on Days 3, 7, 14, and 60. Study participants and independent evaluators are blinded to treatment allocation.

Locations (1)

Hospital Nova

Jyväskylä, Finland, Finland