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Heart Failure With Preserved Ejection Fraction in Patients With Сhronic Obstructive Pulmonary Disease: Clinical Course and Prognosis
Sponsor: National Medical Research Center for Therapy and Preventive Medicine
Summary
Study aim is comparison of heart failire with preserved ejection fraction (HFpEF) detection rate in patients with Сhronic Obstructive Pulmonary Disease (COPD) and the clinical course and prognosis in patients with COPD depending on HFpEF presence.
Key Details
Gender
All
Age Range
50 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2026-01-01
Completion Date
2026-12-31
Last Updated
2026-02-10
Healthy Volunteers
No
Conditions
Interventions
Echocardiography
Transthoracic echocardiography at rest: with determination of epicardial fat tissue thickness, epicardial adipose tissue thickness (EAT), E/e', interventricular septum thickness, left ventricular posterior wall thickness, and end-diastolic dimension
Spirometry
Spirometry is the most common of the pulmonary function tests, which measures the lung capacity and airway patency (volume and speed of air) during quiet and forced breathing.
Body plethysmography
Body plethysmography is a non-invasive lung function test performed in a sealed booth (body box) that measures total lung volume, functional residual capacity, and airway resistance by using Boyle's Law to track pressure and volume changes as a patient breathes, providing crucial data for diagnosing conditions like COPD and asthma, and differentiating them from other lung disorders
6-Minute Walk Test (6MWT)
The 6 Minute Walk Test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity
laboratory biomarker analysis
Routine and special laboratory tests
Locations (2)
Kazan State Medical University
Kazan', Russia
National Medical Research Center for Therapy and Preventive Medicine
Moscow, Russia