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NOT YET RECRUITING
NCT07376486
NA

Duodenal ReCET as an Early Treatment for Type 2 DM

Sponsor: Chinese University of Hong Kong

View on ClinicalTrials.gov

Summary

This study is designed to evaluate the efficacy and safety of endoscopic duodenal re-cellularization therapy in individuals with in patients with a recent diagnosis of type 2 diabetes mellitus (T2DM).

Official title: Duodenal Recellularization Via Electroporation Therapy as an Early Treatment for Type 2 Diabetes Mellitus (DREAM-1 Study)

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2026-03-01

Completion Date

2032-02-28

Last Updated

2026-01-29

Healthy Volunteers

No

Interventions

PROCEDURE

ReCET treatment

The ReCET procedure utilizes the ReCET catheter to deliver non-thermal pulsed electric field to the duodenum to induce cell regeneration. The catheter is introduced to the duodenum through the mouth using a guide wire and the therapy is applied to treat the duodenum under endoscopic visualisation, starting from D4 and repeated proximally. Approximately 10-18 cm of axial length of the duodenum is treated.

Locations (1)

Chinese University of Hong Kong

Shatin, Hong Kong