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Duodenal ReCET as an Early Treatment for Type 2 DM
Sponsor: Chinese University of Hong Kong
Summary
This study is designed to evaluate the efficacy and safety of endoscopic duodenal re-cellularization therapy in individuals with in patients with a recent diagnosis of type 2 diabetes mellitus (T2DM).
Official title: Duodenal Recellularization Via Electroporation Therapy as an Early Treatment for Type 2 Diabetes Mellitus (DREAM-1 Study)
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2026-03-01
Completion Date
2032-02-28
Last Updated
2026-01-29
Healthy Volunteers
No
Interventions
ReCET treatment
The ReCET procedure utilizes the ReCET catheter to deliver non-thermal pulsed electric field to the duodenum to induce cell regeneration. The catheter is introduced to the duodenum through the mouth using a guide wire and the therapy is applied to treat the duodenum under endoscopic visualisation, starting from D4 and repeated proximally. Approximately 10-18 cm of axial length of the duodenum is treated.
Locations (1)
Chinese University of Hong Kong
Shatin, Hong Kong