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Integrated Study on Gut Microbiota, Immune Indicators, and Trace Elements in Children With Respiratory Tract Infections
Sponsor: Min-Tze LIONG
Summary
This observational study aims to investigate the characteristics of gut microbiota and their associations with immune and nutritional indicators in children with different respiratory health statuses. A total of 120 children will be enrolled and categorized into four groups: children with Mycoplasma pneumoniae pneumonia (MPP), children with acute respiratory tract infections without Mycoplasma pneumoniae (NMP), children with recurrent respiratory tract infections (RRTIs), and healthy controls. By comparing gut microbiota composition and diversity, as well as immune- and nutrition-related indicators across groups, this study seeks to clarify the potential role of intestinal dysbiosis and host immune-nutritional interactions in the pathogenesis and clinical manifestations of pediatric respiratory tract infections.
Key Details
Gender
All
Age Range
3 Years - 14 Years
Study Type
OBSERVATIONAL
Enrollment
120
Start Date
2026-01-30
Completion Date
2026-06-30
Last Updated
2026-02-04
Healthy Volunteers
Yes
Conditions
Locations (2)
The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army
Lanzhou, Gansu, China
Universiti Sains Malaysia
Pulau Pinang, Pulau Pinang, Malaysia