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Early Identification of Cardivascular Damage Induced by Chemotherapy and Antineoplastic Treatments in Pediatric Age
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna
Summary
To test whether the implementation of new diagnostic techniques (ultrasonography, speckle tracking, vascular stiffness study, cardiac MRI, and histologic studies) allows in CAYA (Childern, Adolescents, and Young Adults) cancer survivors a more sensitive and earlier identification of cardiovascular damage resulting from antineoplastic therapy that develops either acutely or remotely after completion of antineoplastic therapy.
Key Details
Gender
All
Age Range
0 Years - 18 Years
Study Type
INTERVENTIONAL
Enrollment
400
Start Date
2025-03-17
Completion Date
2028-12-31
Last Updated
2026-02-02
Healthy Volunteers
No
Conditions
Interventions
Parameters of vascular stiffness
VICORDER© is a noninvasive, quick and painless technique to be able to assess vascular elasticity and consists of placing a few sphygmomanometers (the same ones used to measure blood pressure) for a few minutes
Locations (5)
IRCCS - AOU di Bologna -Policlinico di Sant'Orsola UOC Pediatria
Bologna, Bologna, Italy
IRCCS AOU di Bologna -Policlinico di Sant'Orsola UO Cardiochirurgia pediatrica e dell'età evolutiva
Bologna, Bologna, Italy
IRCCS AOU di Bologna -Policlinico di Sant'Orsola UO Oncoematologia Pediatrica
Bologna, Bologna, Italy
IRCCS AOU di Bologna Policlinico di Sant'Orsola UO Cardiologia Pediatria e dell'età evolutiva
Bologna, Bologna, Italy
IRCCS AOU di Bologna Policlinico di Sant'Orsola UO Radiologia, sezione Cardio-Toraco-Vascolare
Bologna, Bologna, Italy