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Efficacy of Silver Diamine Fluoride Versus Nano-Silver Fluoride in Arresting Active Dentin Caries in Primary Teeth in Young Children
Sponsor: October University for Modern Sciences and Arts
Summary
Early childhood caries is a major public health problem affecting preschool children worldwide. Silver Diamine Fluoride is a well-established non-invasive treatment for arresting caries; however, it causes black discoloration of treated lesions. Nano-Silver Fluoride has been introduced as an alternative that may arrest caries without discoloration. This randomized clinical trial aims to compare the efficacy of Silver Diamine Fluoride and Nano-Silver Fluoride in arresting active dentin caries in primary teeth and to assess discoloration, post-operative pain, and parental satisfaction over a 12-month follow-up period.
Official title: Efficacy of Silver Diamine Fluoride Versus Nano-Silver Fluoride in Arresting Active Dentin Caries in Primary Teeth in Young Children: A Randomized Clinical Trial
Key Details
Gender
All
Age Range
3 Years - 5 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-01-30
Completion Date
2026-03-15
Last Updated
2026-02-02
Healthy Volunteers
No
Interventions
Nano-Silver Fluoride
Chitosan (28,585 μg/ml), Silver (376.5 μg/ml) and Sodium fluoride (5028.3 μg/ml)
Silver Diamine Fluoride
38% Silver Diamine Fluoride
Locations (1)
Faculty of Dentistry, MSA University
Giza, Giza Governorate, Egypt