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Intranasal Platelet-Rich Plasma With or Without Topical Insulin for Post-Inflammatory Anosmia
Sponsor: Amin Javer
Summary
This study evaluates whether adding topical insulin to intranasal platelet-rich plasma (PRP) improves smell recovery in adults with post-inflammatory anosmia. Participants will be randomly assigned to receive either intranasal PRP combined with topical insulin or intranasal PRP alone. Changes in olfactory function will be assessed over time to compare the effectiveness and safety of the two treatments.
Official title: Assessing the Effectiveness of Combined Intranasal Platelet-rich Plasma Plus Topical Insulin Versus Platelet-rich Plasma Alone in the Treatment of Post Inflammatory Anosmia: a Randomized Controlled Trial
Key Details
Gender
All
Age Range
19 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-03-30
Completion Date
2027-01-01
Last Updated
2026-02-03
Healthy Volunteers
No
Conditions
Interventions
Intranasal PRP Plus Topical Insulin
Autologous platelet-rich plasma administered intranasally with the addition of topical insulin applied to the olfactory cleft.
Intranasal PRP Plus Saline (Placebo)
Autologous platelet-rich plasma administered intranasally with saline applied in place of topical insulin as a placebo comparator.