Clinical Research Directory
Browse clinical research sites, groups, and studies.
Immune Cells Role in Lung Cancer and Their Use in Anticancer Immunotherapies and Inflammatory Lung Disease
Sponsor: Université Catholique de Louvain
Summary
This study aims to better understand the role of immune system cells in lung diseases such as lung cancer, sarcoidosis, and chronic obstructive pulmonary disease (COPD). The investigators are studying how these immune cells can sometimes help the body defend itself, but in other cases may contribute to cancer growth or long-term lung inflammation. Although recent treatments like immunotherapy have improved cancer care, only a small proportion of patients currently benefit from these therapies. One goal of this research is to understand why some patients do not respond or develop resistance to treatment. The knowledge gained from this study may help researchers develop more effective and personalized treatments for people with lung diseases in the future.
Key Details
Gender
All
Age Range
Any - 80 Years
Study Type
INTERVENTIONAL
Enrollment
425
Start Date
2025-02-17
Completion Date
2032-02-17
Last Updated
2026-02-03
Healthy Volunteers
Yes
Conditions
Interventions
Peripheral Blood Collection for Immune Profiling
Participants provide biological samples for immune profiling and translational research. Samples include peripheral blood and, when available from routine clinical care, additional specimens such as tumor tissue or rlymph node, bone marrow. No experimental treatments are given. Collected samples are analyzed to characterize immune cell populations and their functional and molecular features, with the aim of studying immune mechanisms involved in lung cancer, sarcoidosis, and COPD, as well as factors associated with disease progression and treatment response. All medical care and treatment decisions remain independent of study participation.
Locations (1)
Cliniques universitaires saint Luc
Brussels, Belgium