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OJO-miR: microRNA Expression in Allergic Conjunctivitis.
Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana
Summary
Allergic conjunctivitis (AC) causes inflammation of the conjunctiva in response to environmental allergens, affecting a significant percentage of the world population and reducing quality of life. The pathophysiology is poorly understood, lacking effective treatments. MicroRNAs have potential for diagnosing and characterizing inflammatory diseases. This study aims to compare the expression profiles of inflammation-regulating microRNAs (miR-19, miR-23, miR-125b, miR-146a, and miR-155) in serum and tear samples from subjects with AC and healthy subjects to identify biomarkers and therapeutic targets.
Official title: Analysis of the Expression Profiles of Inflammation-regulating microRNAs in Serum and Tear Samples From Subjects With Allergic Conjunctivitis.
Key Details
Gender
All
Age Range
5 Years - 30 Years
Study Type
OBSERVATIONAL
Enrollment
40
Start Date
2026-01-05
Completion Date
2027-07-05
Last Updated
2026-02-04
Healthy Volunteers
Yes
Conditions
Locations (1)
Instituto de Oftalmología FAP Conde de Valenciana, IAP Sede Centro
Mexico City, Mexico City, Mexico