Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT07388667
PHASE1

A Clinical Study of MK-4082 in Healthy Overweight Participants (MK-4082-002)

Sponsor: Merck Sharp & Dohme LLC

View on ClinicalTrials.gov

Summary

Researchers are looking for new weight loss medicines for people with higher body weight. The study medicine, MK-4082, is different from similar weight loss medicines because people take it as a pill instead of an injection. Before giving a study medicine to people with a health condition, researchers first do studies to find a safe dose level (amount) of the study medicine that can be used in future studies. The goals of this study are to learn about: * The safety of MK-4082 and if people tolerate it * What happens to different MK-4082 dose levels in a person's body over time

Official title: A Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of MK-4082 in Healthy Overweight/Obese Participants

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2026-03-04

Completion Date

2026-08-19

Last Updated

2026-03-30

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

MK-4082

Oral Tablet

DRUG

Placebo

Oral Tablet

Locations (5)

Anaheim Clinical Trials ( Site 0005)

Anaheim, California, United States

ProSciento Inc. ( Site 0002)

Chula Vista, California, United States

QPS-MRA, LLC ( Site 0003)

South Miami, Florida, United States

Bio-Kinetic Clinical Applications, LLD dba QPS-MO ( Site 0004)

Springfield, Missouri, United States

Hassman Research Institute Marlton Site ( Site 0006)

Marlton, New Jersey, United States