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Exercise, Chronotype, and Prediabetes
Sponsor: German Diabetes Center
Summary
The goal of this clinical trial is to find out whether exercising at the right time of day, based on a person's natural body clock, leads to greater health benefits in people living with prediabetes. The main question it aims to answer is whether doing a single session of exercise in the morning or in the evening affects how the body handles sugar differently in adults with prediabetes who have an extreme natural body clock. This will be done by comparing three conditions (no-exercise, morning exercise, and evening exercise) within the same participant. Each condition will be tested on a different day, with at least 14 days between the test days. During the no-exercise test days, participants will come to the study centre and will only be allowed to do sedentary activities (e.g. office work, reading, or screen time). During the morning exercise test days, participants will perform an exercise session at 9:00 am that involves short periods of very hard effort followed by short rest periods. Whereas for the evening exercise test days, the same type of exercise will be performed at 5:00 pm.
Official title: Timed Exercise in Prediabetes With Extreme Chronotype
Key Details
Gender
All
Age Range
19 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
28
Start Date
2026-02
Completion Date
2028-08
Last Updated
2026-02-05
Healthy Volunteers
No
Conditions
Interventions
Timing of exercise
An acute exercise bout of cycling performed in the morning at 9 AM
Timing of exercise
An acute exercise bout of cycling performed in the morning at at 5 PM
Control
No exercise
Locations (1)
German Diabetes Center (DDZ)
Düsseldorf, Germany