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ACTIVE NOT RECRUITING
NCT07389447
NA

Focused Ultrasound Stimulation of the Cerebellum to Induce Changes in Cognition and Brain Activity

Sponsor: University of Nottingham

View on ClinicalTrials.gov

Summary

The goal of this preclinical study is to assess the effects of focused ultrasound stimulation to the cerebellum on brain dynamics and cognition in healthy volunteers aged 18 to 40. The main questions it aims to answer are: Does FUS applied to the cerebellum affect cognition? Does FUS applied to the white matter or gray matter of the cerebellum with the same parameters result in different outcomes? Researchers will compare active and sham stimulations. Participants will be asked to complete cognitive tasks after receiving FUS to the cerebellum.

Official title: FUS of the Dentate Nucleus and Superior Cerebellar Peduncle of the Cerebellum Induces Changes to EEG Power Bands, Spatiotemporal Dynamics, and Cognitive Function in Healthy Humans

Key Details

Gender

All

Age Range

18 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2024-02-05

Completion Date

2026-07-31

Last Updated

2026-02-05

Healthy Volunteers

Yes

Interventions

PROCEDURE

Focused ultrasound

Focused ultrasound stimulation administered to the cerebellar nucleus or efferent fiber tract.

DIAGNOSTIC_TEST

EEG

This is the electroencephalography reading that will show changes in brain activity as describes in outcome measures

Locations (1)

Precision Medical Imaging, QMC

Nottingham, Nottinghamshire, United Kingdom