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Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)
Sponsor: Brigham and Women's Hospital
Summary
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
25664
Start Date
2026-01-24
Completion Date
2026-05-11
Last Updated
2026-03-12
Healthy Volunteers
No
Conditions
Interventions
Oral semaglutide
Initiation of semaglutide dispensing claim is used as the exposure.
Sitagliptin
Initiation of sitagliptin dispensing claim is used as the reference.
Locations (1)
Brigham and Women's Hospital
Boston, Massachusetts, United States